Reaction Details |
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Target | Vasopressin V2 receptor |
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Ligand | BDBM81890 |
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Substrate/Competitor | n/a |
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Ki | 3100±n/a nM |
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Comments | PDSP_1040 |
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Citation | Pettibone, DJ; Clineschmidt, BV; Lis, EV; Reiss, DR; Totaro, JA; Woyden, CJ; Bock, MG; Freidinger, RM; Tung, RD; Veber, DF In vitro pharmacological profile of a novel structural class of oxytocin antagonists. J Pharmacol Exp Ther256:304-8 (1991) [PubMed] |
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More Info.: | Get all data from this article |
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Vasopressin V2 receptor |
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Name: | Vasopressin V2 receptor |
Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
Type: | G-protein coupled receptor |
Mol. Mass.: | 40761.85 |
Organism: | Rattus norvegicus (Rat) |
Description: | n/a |
Residue: | 371 |
Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
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BDBM81890 |
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n/a |
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Name | BDBM81890 |
Synonyms: | CAS_196819 | L-366,682 | NSC_196819 |
Type | Small organic molecule |
Emp. Form. | C40H53N9O6 |
Mol. Mass. | 755.9055 |
SMILES | CC(C=C)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C1CCCN1C(=O)C(N)Cc1cnc[nH]1)C(=O)N1CCCCC1(C=O)C(=O)N1CCCCC1 |
Structure |
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