Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Vasopressin V2 receptor |
---|
Ligand | BDBM81892 |
---|
Substrate/Competitor | n/a |
---|
Ki | 550±n/a nM |
---|
Comments | PDSP_1041 |
---|
Citation | Pettibone, DJ; Clineschmidt, BV; Lis, EV; Reiss, DR; Totaro, JA; Woyden, CJ; Bock, MG; Freidinger, RM; Tung, RD; Veber, DF In vitro pharmacological profile of a novel structural class of oxytocin antagonists. J Pharmacol Exp Ther256:304-8 (1991) [PubMed] |
---|
More Info.: | Get all data from this article |
---|
|
Vasopressin V2 receptor |
---|
Name: | Vasopressin V2 receptor |
Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
Type: | G-protein coupled receptor |
Mol. Mass.: | 40761.85 |
Organism: | Rattus norvegicus (Rat) |
Description: | n/a |
Residue: | 371 |
Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
|
|
|
BDBM81892 |
---|
n/a |
---|
Name | BDBM81892 |
Synonyms: | Cyclo[L-Pro-D-Phe-L-Ile-1,6-didehydro-D-Pyz-N-methyl-D-Phe-] | J440.774A | L-366,706 |
Type | Small organic molecule |
Emp. Form. | C35H44N6O5 |
Mol. Mass. | 628.7611 |
SMILES | CCC(C)C1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]2CCCN2C(=O)C(Cc2ccccc2)N(C)C(=O)[C@H]2CCC=NN2C1=O |c:44| |
Structure |
|