| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
|---|
| Ligand | BDBM50003666 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_49567 |
|---|
| IC50 | 1900±n/a nM |
|---|
| Citation |  Tilley, JW; Danho, W; Madison, V; Fry, D; Swistok, J; Makofske, R; Michalewsky, J; Schwartz, A; Weatherford, S; Triscari, J Analogs of CCK incorporating conformationally constrained replacements for Asp32. J Med Chem35:4249-52 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cholecystokinin receptor type A |
|---|
| Name: | Cholecystokinin receptor type A |
|---|
| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_HUMAN | CCKRA | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 Receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 47859.34 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Stable expression of human CCK-1 receptors in HEK 293 cells. |
|---|
| Residue: | 428 |
|---|
| Sequence: | MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
MSASVPPQ
|
|
|
|---|
| BDBM50003666 |
|---|
| n/a |
|---|
| Name | BDBM50003666 |
|---|
| Synonyms: | 3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid | CHEMBL323521 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C44H56N8O9 |
|---|
| Mol. Mass. | 840.9636 |
|---|
| SMILES | CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
