Reaction Details | |||
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Target | Cyclin-dependent kinase 12 | ||
Ligand | BDBM50367955 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1735959 (CHEMBL4151495) | ||
IC50 | 110±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Cyclin-dependent kinase 12 | |||
Name: | Cyclin-dependent kinase 12 | ||
Synonyms: | 2.7.11.22 | 2.7.11.23 | CDC2-related protein kinase 7 | CDK12 | CDK12_HUMAN | CRK7 | CRKRS | Cdc2-related kinase, arginine/serine-rich | Cell division cycle 2-related protein kinase 7 | Cell division protein kinase 12 | Cyclin-dependent kinase 12 | KIAA0904 | hCDK12 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 164218.64 | ||
Organism: | Homo sapiens | ||
Description: | ChEMBL_117739 | ||
Residue: | 1490 | ||
Sequence: |
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BDBM50367955 | |||
n/a | |||
Name | BDBM50367955 | ||
Synonyms: | CHEMBL4174716 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H26N6O2S | ||
Mol. Mass. | 450.557 | ||
SMILES | Cn1cc(cn1)-c1ccc(cc1)N([C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C#N)S(C)(=O)=O |r,wU:13.14,wD:16.21,(31.03,-25.96,;29.49,-26.06,;28.51,-24.88,;27.08,-25.45,;27.17,-26.98,;28.67,-27.36,;25.77,-24.62,;25.84,-23.08,;24.54,-22.26,;23.17,-22.98,;23.11,-24.52,;24.41,-25.34,;21.86,-22.15,;20.54,-22.94,;20.56,-24.48,;19.23,-25.27,;17.89,-24.52,;17.87,-22.98,;19.19,-22.19,;16.57,-25.3,;15.22,-24.55,;13.9,-25.34,;12.55,-24.58,;12.53,-23.04,;13.86,-22.26,;15.2,-23.01,;11.19,-22.29,;9.84,-21.53,;21.93,-20.61,;23.25,-19.82,;20.58,-19.86,;21.53,-19.11,)| | ||
Structure | ![]() |