| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 4 |
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| Ligand | BDBM50451372 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1745058 (CHEMBL4179568) |
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| IC50 | 100±n/a nM |
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| Citation |  Banno, Y; Sasaki, S; Kamata, M; Kunitomo, J; Miyamoto, Y; Abe, H; Taya, N; Oi, S; Watanabe, M; Urushibara, T; Hazama, M; Niwa, SI; Miyamoto, S; Horinouchi, A; Kuroshima, KI; Amano, N; Matsumoto, SI; Matsunaga, S Design and synthesis of a novel series of orally active, selective somatostatin receptor 2 agonists for the treatment of type 2 diabetes. Bioorg Med Chem25:5995-6006 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 4 |
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| Name: | Somatostatin receptor type 4 |
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| Synonyms: | SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42015.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P31391 |
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| Residue: | 388 |
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| Sequence: | MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR
AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP
IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA
VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILS
YANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM
CPPLPCQQEALQPEPGRKRIPLTRTTTF
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| BDBM50451372 |
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| n/a |
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| Name | BDBM50451372 |
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| Synonyms: | CHEMBL4217405 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H36F4N6O4 |
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| Mol. Mass. | 668.6811 |
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| SMILES | C[C@H]([C@@H](NC(=O)N1CCN(C(=O)C1)c1ccc(F)cc1C)C(=O)Nc1cc(CN(C)C)ccc1OC(F)(F)F)c1c[nH]c2ccccc12 |r| |
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| Structure | 
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