| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50461092 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1770714 (CHEMBL4222826) |
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| IC50 | 2170±n/a nM |
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| Citation |  Cui, G; Jin, J; Chen, H; Cao, R; Chen, X; Xu, B Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors. Bioorg Med Chem26:2186-2197 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50461092 |
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| n/a |
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| Name | BDBM50461092 |
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| Synonyms: | CHEMBL4227633 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10ClN5O3 |
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| Mol. Mass. | 331.714 |
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| SMILES | Cn1nc(cc1Oc1nc(Cl)ncc1[N+]([O-])=O)-c1ccccc1 |
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| Structure | 
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