Reaction Details |
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Target | Sigma intracellular receptor 2 |
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Ligand | BDBM50464852 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1783007 (CHEMBL4254524) |
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Ki | 96±n/a nM |
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Citation | Temme, L; Frehland, B; Schepmann, D; Robaa, D; Sippl, W; Wünsch, B Hydroxymethyl bioisosteres of phenolic GluN2B-selective NMDA receptor antagonists: Design, synthesis and pharmacological evaluation. Eur J Med Chem144:672-681 (2018) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma intracellular receptor 2 |
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Name: | Sigma intracellular receptor 2 |
Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
Type: | Protein |
Mol. Mass.: | 20953.88 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q5U3Y7 |
Residue: | 176 |
Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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BDBM50464852 |
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n/a |
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Name | BDBM50464852 |
Synonyms: | CHEMBL4284348 |
Type | Small organic molecule |
Emp. Form. | C21H27NO |
Mol. Mass. | 309.4452 |
SMILES | Oc1ccc2CCC(CCc2c1)NCCCCc1ccccc1 |
Structure |
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