Compile Data Set for Download or QSAR

Found 1037 hits with Last Name = 'robaa' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50499215 (CHEMBL3735947) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCc1ccccc1 Show InChI InChI=1S/C20H24N2O2/c23-22(24)20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21H,4,7-9,11-12,14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50551241 (CHEMBL4746028) Show SMILES C1Cc2ccccc2CC1N1CCC(CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50551242 (CHEMBL4740593) Show SMILES C(C1CCN(CC1)C1CCc2ccccc2C1)c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50313917 (6-Methyl-5,6,7,8,13,15-hexahydro-4H-indolo[4,3a,3-...) Show SMILES CN1CCc2ccccc2Cc2c[nH]c3cccc(CC1)c23 Show InChI InChI=1S/C20H22N2/c1-22-11-9-15-5-2-3-6-17(15)13-18-14-21-19-8-4-7-16(10-12-22)20(18)19/h2-8,14,21H,9-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]radioligand from human recombinant dopamine D5 receptor expressed in HEK293 cells by microplate scintillation counting				J Med Chem 53: 2646-50 (2010) Article DOI: 10.1021/jm901291r BindingDB Entry DOI: 10.7270/Q2SJ1KRJ
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50551241 (CHEMBL4746028) Show SMILES C1Cc2ccccc2CC1N1CCC(CC1)c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50551246 (CHEMBL4758763) Show SMILES C(C1CCN(CC1)C1Cc2ccccc2C1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50499214 (CHEMBL3735485) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCc1ccccc1 Show InChI InChI=1S/C19H22N2O2/c22-21(23)19-11-8-16-6-9-18(10-7-17(16)14-19)20-13-12-15-4-2-1-3-5-15/h1-5,8,11,14,18,20H,6-7,9-10,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50499212 (CHEMBL3736502) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O2/c24-23(25)21-14-11-18-9-12-20(13-10-19(18)16-21)22-15-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,11,14,16,20,22H,4-5,8-10,12-13,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50313917 (6-Methyl-5,6,7,8,13,15-hexahydro-4H-indolo[4,3a,3-...) Show SMILES CN1CCc2ccccc2Cc2c[nH]c3cccc(CC1)c23 Show InChI InChI=1S/C20H22N2/c1-22-11-9-15-5-2-3-6-17(15)13-18-14-21-19-8-4-7-16(10-12-22)20(18)19/h2-8,14,21H,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human recombinant dopamine D2L receptor expressed in HEK293 cells by microplate scintillation counting				J Med Chem 53: 2646-50 (2010) Article DOI: 10.1021/jm901291r BindingDB Entry DOI: 10.7270/Q2SJ1KRJ
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50313917 (6-Methyl-5,6,7,8,13,15-hexahydro-4H-indolo[4,3a,3-...) Show SMILES CN1CCc2ccccc2Cc2c[nH]c3cccc(CC1)c23 Show InChI InChI=1S/C20H22N2/c1-22-11-9-15-5-2-3-6-17(15)13-18-14-21-19-8-4-7-16(10-12-22)20(18)19/h2-8,14,21H,9-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human recombinant dopamine D1 receptor expressed in HEK293 cells by microplate scintillation counting				J Med Chem 53: 2646-50 (2010) Article DOI: 10.1021/jm901291r BindingDB Entry DOI: 10.7270/Q2SJ1KRJ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50363963 (CHEMBL1949725) Show SMILES C[C@H]1Cc2c(Cc3ccccc3CCN1C)[nH]c1ccccc21 |r| Show InChI InChI=1S/C21H24N2/c1-15-13-19-18-9-5-6-10-20(18)22-21(19)14-17-8-4-3-7-16(17)11-12-23(15)2/h3-10,15,22H,11-14H2,1-2H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cells				J Med Chem 54: 7422-6 (2011) Article DOI: 10.1021/jm200676f BindingDB Entry DOI: 10.7270/Q27M08DP
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50551245 (CHEMBL4745685) Show SMILES C1C(Cc2ccccc12)N1CCC(CC1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50602203 (CHEMBL5171086) Show SMILES CCCNNC(=O)c1cnc(nc1)N1CCN(Cc2c[nH]c3ccccc23)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01132 BindingDB Entry DOI: 10.7270/Q2959NMG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50551242 (CHEMBL4740593) Show SMILES C(C1CCN(CC1)C1CCc2ccccc2C1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50363963 (CHEMBL1949725) Show SMILES C[C@H]1Cc2c(Cc3ccccc3CCN1C)[nH]c1ccccc21 |r| Show InChI InChI=1S/C21H24N2/c1-15-13-19-18-9-5-6-10-20(18)22-21(19)14-17-8-4-3-7-16(17)11-12-23(15)2/h3-10,15,22H,11-14H2,1-2H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cells				J Med Chem 54: 7422-6 (2011) Article DOI: 10.1021/jm200676f BindingDB Entry DOI: 10.7270/Q27M08DP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115146 BindingDB Entry DOI: 10.7270/Q2KK9G39
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain cortex membranes incubated for 120 mins measured for 5 mins by scintil...				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50499213 (CHEMBL3735173) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCc1ccccc1 Show InChI InChI=1S/C18H20N2O2/c21-20(22)18-11-8-15-6-9-17(10-7-16(15)12-18)19-13-14-4-2-1-3-5-14/h1-5,8,11-12,17,19H,6-7,9-10,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50551242 (CHEMBL4740593) Show SMILES C(C1CCN(CC1)C1CCc2ccccc2C1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50551241 (CHEMBL4746028) Show SMILES C1Cc2ccccc2CC1N1CCC(CC1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50007677 ((+)-threo 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy...) Show SMILES C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50083351 ((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...) Show SMILES CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50037709 (CHEMBL3357784) Show SMILES COc1ccc2CCC(CCc2c1)NCCCc1ccccc1 Show InChI InChI=1S/C21H27NO/c1-23-21-14-11-18-9-12-20(13-10-19(18)16-21)22-15-5-8-17-6-3-2-4-7-17/h2-4,6-7,11,14,16,20,22H,5,8-10,12-13,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50083351 ((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...) Show SMILES CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from GluN2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes incubated for 120 mins measured for 5 m...				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50331291 ((+/-)-3-(4-Phenylbutyl)-2,3,4,5-tetrahydro-1H-3-be...) Show SMILES OC1CN(CCCCc2ccccc2)CCc2cc(O)ccc12 Show InChI InChI=1S/C20H25NO2/c22-18-9-10-19-17(14-18)11-13-21(15-20(19)23)12-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9-10,14,20,22-23H,4-5,8,11-13,15H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to Sigma 2 receptor (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50313916 (7-Methyl-6,7,8,9,10,15-hexahydroindolo[2,3-f][3]be...) Show SMILES CN1CCc2[nH]c3ccccc3c2Cc2ccccc2CC1 Show InChI InChI=1S/C20H22N2/c1-22-12-10-15-6-2-3-7-16(15)14-18-17-8-4-5-9-19(17)21-20(18)11-13-22/h2-9,21H,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]radioligand from human recombinant dopamine D5 receptor expressed in HEK293 cells by microplate scintillation counting				J Med Chem 53: 2646-50 (2010) Article DOI: 10.1021/jm901291r BindingDB Entry DOI: 10.7270/Q2SJ1KRJ
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50363966 (CHEMBL1949728) Show SMILES CN1CCc2ccccc2Cc2[nH]c3ccccc3c2C[C@@H]1CO |r| Show InChI InChI=1S/C21H24N2O/c1-23-11-10-15-6-2-3-7-16(15)12-21-19(13-17(23)14-24)18-8-4-5-9-20(18)22-21/h2-9,17,22,24H,10-14H2,1H3/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cells				J Med Chem 54: 7422-6 (2011) Article DOI: 10.1021/jm200676f BindingDB Entry DOI: 10.7270/Q27M08DP
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50363966 (CHEMBL1949728) Show SMILES CN1CCc2ccccc2Cc2[nH]c3ccccc3c2C[C@@H]1CO |r| Show InChI InChI=1S/C21H24N2O/c1-23-11-10-15-6-2-3-7-16(15)12-21-19(13-17(23)14-24)18-8-4-5-9-20(18)22-21/h2-9,17,22,24H,10-14H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin Luther Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cells				J Med Chem 54: 7422-6 (2011) Article DOI: 10.1021/jm200676f BindingDB Entry DOI: 10.7270/Q27M08DP
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50079387 (1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...) Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from GluN2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes incubated for 120 mins measured for 5 m...				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50079387 (1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...) Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 2 hrs by scintillation c...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50079387 (1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...) Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50464851 (CHEMBL4294561) Show SMILES COc1ccc2[C@H](O)C[C@@H](CCc2c1)NCCCc1ccccc1 |r| Show InChI InChI=1S/C21H27NO2/c1-24-19-11-12-20-17(14-19)9-10-18(15-21(20)23)22-13-5-8-16-6-3-2-4-7-16/h2-4,6-7,11-12,14,18,21-23H,5,8-10,13,15H2,1H3/t18-,21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from GluN2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50551236 (CHEMBL4754021) Show SMILES C(CN1CCCc2ccccc2CC1)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50499215 (CHEMBL3735947) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCc1ccccc1 Show InChI InChI=1S/C20H24N2O2/c23-22(24)20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21H,4,7-9,11-12,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50499214 (CHEMBL3735485) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCc1ccccc1 Show InChI InChI=1S/C19H22N2O2/c22-21(23)19-11-8-16-6-9-18(10-7-17(16)14-19)20-13-12-15-4-2-1-3-5-15/h1-5,8,11,14,18,20H,6-7,9-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50464852 (CHEMBL4284348) Show SMILES Oc1ccc2CCC(CCc2c1)NCCCCc1ccccc1 Show InChI InChI=1S/C21H27NO/c23-21-14-11-18-9-12-20(13-10-19(18)16-21)22-15-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,11,14,16,20,22-23H,4-5,8-10,12-13,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from GluN2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50499213 (CHEMBL3735173) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCc1ccccc1 Show InChI InChI=1S/C18H20N2O2/c21-20(22)18-11-8-15-6-9-17(10-7-16(15)12-18)19-13-14-4-2-1-3-5-14/h1-5,8,11-12,17,19H,6-7,9-10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50551237 (CHEMBL4778291) Show SMILES C(CCc1ccccc1)CN1CCCc2ccccc2CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50499212 (CHEMBL3736502) Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O2/c24-23(25)21-14-11-18-9-12-20(13-10-19(18)16-21)22-15-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,11,14,16,20,22H,4-5,8-10,12-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Munster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis				Bioorg Med Chem Lett 25: 5748-51 (2015) Article DOI: 10.1016/j.bmcl.2015.10.076 BindingDB Entry DOI: 10.7270/Q2639SQV
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50551245 (CHEMBL4745685) Show SMILES C1C(Cc2ccccc12)N1CCC(CC1)c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50504632 (CHEMBL4561134) Show SMILES Cl.OC1CC(CCc2ccccc12)NCCCc1ccccc1 Show InChI InChI=1S/C20H25NO.ClH/c22-20-15-18(13-12-17-10-4-5-11-19(17)20)21-14-6-9-16-7-2-1-3-8-16;/h1-5,7-8,10-11,18,20-22H,6,9,12-15H2;1H	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranes measured after 120 mins by solid scintillation counting method				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115146 BindingDB Entry DOI: 10.7270/Q2KK9G39
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50464853 (CHEMBL4286654) Show SMILES Oc1ccc2CCC(CCc2c1)NCCCc1ccccc1 Show InChI InChI=1S/C20H25NO/c22-20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21-22H,4,7-9,11-12,14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from GluN2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50551246 (CHEMBL4758763) Show SMILES C(C1CCN(CC1)C1Cc2ccccc2C1)c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50313916 (7-Methyl-6,7,8,9,10,15-hexahydroindolo[2,3-f][3]be...) Show SMILES CN1CCc2[nH]c3ccccc3c2Cc2ccccc2CC1 Show InChI InChI=1S/C20H22N2/c1-22-12-10-15-6-2-3-7-16(15)14-18-17-8-4-5-9-19(17)21-20(18)11-13-22/h2-9,21H,10-14H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human recombinant dopamine D1 receptor expressed in HEK293 cells by microplate scintillation counting				J Med Chem 53: 2646-50 (2010) Article DOI: 10.1021/jm901291r BindingDB Entry DOI: 10.7270/Q2SJ1KRJ
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50006980 ((3-Phenyl-propyl)-(1,2,3,4-tetrahydro-naphthalen-2...) Show SMILES C(CNC1CCc2ccccc2C1)Cc1ccccc1 Show InChI InChI=1S/C19H23N/c1-2-7-16(8-3-1)9-6-14-20-19-13-12-17-10-4-5-11-18(17)15-19/h1-5,7-8,10-11,19-20H,6,9,12-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50602192 (CHEMBL5174998) Show SMILES CCCCCCNNC(=O)c1ccc(cc1)-c1ccc(CNC(C)=O)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01132 BindingDB Entry DOI: 10.7270/Q2959NMG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50551244 (CHEMBL4800530) Show SMILES C(CCc1ccccc1)CNC1Cc2ccccc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112138 BindingDB Entry DOI: 10.7270/Q2D50RKS
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50464853 (CHEMBL4286654) Show SMILES Oc1ccc2CCC(CCc2c1)NCCCc1ccccc1 Show InChI InChI=1S/C20H25NO/c22-20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21-22H,4,7-9,11-12,14H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes incubated for 120 mins measured for 5 mins by scintillation cou...				Eur J Med Chem 144: 672-681 (2018) Article DOI: 10.1016/j.ejmech.2017.12.054 BindingDB Entry DOI: 10.7270/Q2B56NDZ
					More data for this Ligand-Target Pair

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