| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
|---|
| Ligand | BDBM50006980 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2031062 (CHEMBL4685220) |
|---|
| Ki | 29±n/a nM |
|---|
| Citation |  Temme, L; Bechthold, E; Schreiber, JA; Gawaskar, S; Schepmann, D; Robaa, D; Sippl, W; Seebohm, G; Wünsch, B Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds. Eur J Med Chem190:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma intracellular receptor 2 |
|---|
| Name: | Sigma intracellular receptor 2 |
|---|
| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 20953.88 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q5U3Y7 |
|---|
| Residue: | 176 |
|---|
| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
|
|
|
|---|
| BDBM50006980 |
|---|
| n/a |
|---|
| Name | BDBM50006980 |
|---|
| Synonyms: | (3-Phenyl-propyl)-(1,2,3,4-tetrahydro-naphthalen-2-yl)-amine | CHEMBL25858 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H23N |
|---|
| Mol. Mass. | 265.3926 |
|---|
| SMILES | C(CNC1CCc2ccccc2C1)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
