| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50499212 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1538268 (CHEMBL3737380) |
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| Ki | 24±n/a nM |
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| Citation |  Gawaskar, S; Schepmann, D; Bonifazi, A; Robaa, D; Sippl, W; Wünsch, B Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position. Bioorg Med Chem Lett25:5748-51 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50499212 |
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| n/a |
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| Name | BDBM50499212 |
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| Synonyms: | CHEMBL3736502 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O2 |
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| Mol. Mass. | 338.4433 |
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| SMILES | [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCCc1ccccc1 |
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| Structure | 
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