| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50551245 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2031062 (CHEMBL4685220) |
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| Ki | 25±n/a nM |
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| Citation |  Temme, L; Bechthold, E; Schreiber, JA; Gawaskar, S; Schepmann, D; Robaa, D; Sippl, W; Seebohm, G; Wünsch, B Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds. Eur J Med Chem190:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20953.88 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5U3Y7 |
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| Residue: | 176 |
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| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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| BDBM50551245 |
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| n/a |
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| Name | BDBM50551245 |
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| Synonyms: | CHEMBL4745685 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N |
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| Mol. Mass. | 277.4033 |
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| SMILES | C1C(Cc2ccccc12)N1CCC(CC1)c1ccccc1 |
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| Structure | 
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