| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM50240485 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1791804 (CHEMBL4263723) |
|---|
| Ki | 4400±n/a nM |
|---|
| Citation |  Loesche, A; Wiemann, J; Al Halabi, Z; Karasch, J; Sippl, W; Csuk, R Unexpected AChE inhibitory activity of (2E)?,?-unsaturated fatty acids. Bioorg Med Chem Lett28:3315-3319 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | ACES_ELEEL | Acetylcholinesterase (AChE) | Acetylcholinesterase (EeAChE) | ache |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 71812.79 |
|---|
| Organism: | Electrophorus electricus (Electric eel) |
|---|
| Description: | n/a |
|---|
| Residue: | 633 |
|---|
| Sequence: | MKILDALLFPVIFIMFFIHLSIAQTDPELTIMTRLGQVQGTRLPVPDRSHVIAFLGIPFA
EPPLGKMRFKPPEPKKPWNDVFDARDYPSACYQYVDTSYPGFSGTEMWNPNRMMSEDCLY
LNVWVPATPRPHNLTVMVWIYGGGFYSGSSSLDVYDGRYLAHSEKVVVVSMNYRVSAFGF
LALNGSAEAPGNVGLLDQRLALQWVQDNIHFFGGNPKQVTIFGESAGAASVGMHLLSPDS
RPKFTRAILQSGVPNGPWRTVSFDEARRRAIKLGRLVGCPDGNDTDLIDCLRSKQPQDLI
DQEWLVLPFSGLFRFSFVPVIDGVVFPDTPEAMLNSGNFKDTQILLGVNQNEGSYFLIYG
APGFSKDNESLITREDFLQGVKMSVPHANEIGLEAVILQYTDWMDEDNPIKNREAMDDIV
GDHNVVCPLQHFAKMYAQYSILQGQTGTASQGNLGWGNSGSASNSGNSQVSVYLYMFDHR
ASNLVWPEWMGVIHGYEIEFVFGLPLEKRLNYTLEEEKLSRRMMKYWANFARTGNPNINV
DGSIDSRRRWPVFTSTEQKHVGLNTDSLKVHKGLKSQFCALWNRFLPRLLNVTENIDDAE
RQWKAEFHRWSSYMMHWKNQFDHYSKQERCTNL
|
|
|
|---|
| BDBM50240485 |
|---|
| n/a |
|---|
| Name | BDBM50240485 |
|---|
| Synonyms: | 18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Octadecanoic acid | Octadecansaeure | Oktadekansaeure | Stearinsaeure | acide octadecanoique | acide stearique | n-octadecanoic acid | octadecoic acid | stearic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H36O2 |
|---|
| Mol. Mass. | 284.4772 |
|---|
| SMILES | CCCCCCCCCCCCCCCCCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
