| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight protein-tyrosine phosphatase A |
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| Ligand | BDBM50466482 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1793230 (CHEMBL4265149) |
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| IC50 | 9100±n/a nM |
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| Citation |  Sens, L; de Souza, ACA; Pacheco, LA; Menegatti, ACO; Mori, M; Mascarello, A; Nunes, RJ; Terenzi, H Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors. Bioorg Med Chem26:5742-5750 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Low molecular weight protein-tyrosine phosphatase A |
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| Name: | Low molecular weight protein-tyrosine phosphatase A |
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| Synonyms: | PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA |
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| Type: | Hydrolase |
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| Mol. Mass.: | 17891.84 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | n/a |
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| Residue: | 163 |
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| Sequence: | MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAG
VLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTH
ALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
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| BDBM50466482 |
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| n/a |
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| Name | BDBM50466482 |
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| Synonyms: | CHEMBL4282817 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15ClF3N3OS |
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| Mol. Mass. | 437.866 |
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| SMILES | Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 |
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| Structure | 
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