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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cholecystokinin receptor type A | ||
| Ligand | BDBM50471074 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_49876 (CHEMBL663392) | ||
| Ki | 8128±n/a nM | ||
| Citation |  Kalindjian, SB; Buck, IM; Davies, JM; Dunstone, DJ; Hudson, ML; Low, CM; McDonald, IM; Pether, MJ; Steel, KI; Tozer, MJ; Vinter, JG Non-peptide cholecystokinin-B/gastrin receptor antagonists based on bicyclic, heteroaromatic skeletons. J Med Chem39:1806-15 (1996) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cholecystokinin receptor type A | |||
| Name: | Cholecystokinin receptor type A | ||
| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor | ||
| Type: | n/a | ||
| Mol. Mass.: | 48229.77 | ||
| Organism: | Cavia porcellus | ||
| Description: | n/a | ||
| Residue: | 430 | ||
| Sequence: |
| ||
| BDBM50471074 | |||
| n/a | |||
| Name | BDBM50471074 | ||
| Synonyms: | CHEMBL301740 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H38N2O4 | ||
| Mol. Mass. | 538.6765 | ||
| SMILES | OC(=O)[C@H]1CCCN1C(=O)C1C(C2c3ccccc3C1c1ccccc21)C(=O)NCC12CC3CC(CC(C3)C1)C2 |wD:3.2,TLB:8:10:13.18:25.20,24:25:10.11:13.18,21:20:10.11:13.18,37:36:39:32.31.33,37:32:39:36.38.35,26:11:13.18:25.20,14:13:10.11:25.20,THB:35:36:31:34.39.33,35:34:31:36.38.37,17:18:10.11:25.20,(9.17,-4.52,;7.61,-4.52,;7.6,-6.09,;6.26,-3.73,;7.42,-2.7,;6.78,-1.26,;5.24,-1.43,;4.91,-2.96,;3.35,-2.96,;3.75,-1.44,;1.78,-2.96,;2.59,-2.09,;2.59,-3.11,;4.15,-3.87,;5.52,-3.84,;6.11,-5,;5.33,-6.16,;3.95,-6.14,;3.37,-5,;1.8,-4.22,;.17,-5.22,;-1.25,-5.3,;-1.93,-4.15,;-1.18,-2.94,;.24,-2.85,;.92,-4.01,;3.18,-.65,;2.21,.58,;4.72,-.43,;5.83,.68,;7.4,.68,;7.44,2.22,;8.91,2.74,;9.73,1.53,;9.73,.09,;11.37,-.59,;10.44,.69,;10.48,2.23,;8.94,.12,;8.32,-.43,)| | ||
| Structure | 
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