Reaction Details |
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Target | Similar to alpha-tubulin isoform 1 |
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Ligand | BDBM50472346 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_211318 (CHEMBL818978) |
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IC50 | 1200±n/a nM |
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Citation | Zhang, SX; Bastow, KF; Tachibana, Y; Kuo, SC; Hamel, E; Mauger, A; Narayanan, VL; Lee, KH Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. J Med Chem42:4081-7 (1999) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Similar to alpha-tubulin isoform 1 |
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Name: | Similar to alpha-tubulin isoform 1 |
Synonyms: | Similar to alpha-tubulin isoform 1 |
Type: | PROTEIN |
Mol. Mass.: | 10383.05 |
Organism: | Bos taurus |
Description: | ChEMBL_104716 |
Residue: | 99 |
Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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BDBM50472346 |
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n/a |
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Name | BDBM50472346 |
Synonyms: | CHEMBL423514 |
Type | Small organic molecule |
Emp. Form. | C17H12N2OS |
Mol. Mass. | 292.355 |
SMILES | Cc1ccnc2nc(cc(O)c12)-c1csc2ccccc12 |
Structure |
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