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Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Integrase | ||
| Ligand | BDBM50479060 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_509632 (CHEMBL1003960) | ||
| IC50 | >100000±n/a nM | ||
| Citation |  Zeng, LF; Jiang, XH; Sanchez, T; Zhang, HS; Dayam, R; Neamati, N; Long, YQ Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation. Bioorg Med Chem16:7777-87 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Integrase | |||
| Name: | Integrase | ||
| Synonyms: | pol | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 32203.43 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_106649 | ||
| Residue: | 288 | ||
| Sequence: |
| ||
| BDBM50479060 | |||
| n/a | |||
| Name | BDBM50479060 | ||
| Synonyms: | CHEMBL469070 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H24F2N2O6 | ||
| Mol. Mass. | 498.4754 | ||
| SMILES | Fc1ccc(cc1)C(=O)CC(=O)C(=O)NC1CCC(CC1)NC(=O)C(=O)CC(=O)c1ccc(F)cc1 |(8.82,-41.88,;10.15,-42.65,;11.48,-41.88,;12.81,-42.65,;12.81,-44.19,;11.49,-44.96,;10.16,-44.2,;14.14,-44.96,;14.14,-46.5,;15.47,-44.19,;16.81,-44.96,;16.82,-46.51,;18.15,-44.19,;18.15,-42.65,;19.48,-44.96,;20.8,-44.15,;22.14,-44.88,;23.46,-44.08,;23.42,-42.55,;22.07,-41.81,;20.74,-42.61,;24.73,-41.75,;24.69,-40.21,;23.34,-39.46,;26.01,-39.4,;27.36,-40.13,;25.96,-37.86,;27.28,-37.05,;28.63,-37.79,;27.24,-35.51,;28.55,-34.72,;28.52,-33.19,;27.16,-32.46,;27.13,-30.92,;25.85,-33.26,;25.89,-34.8,)| | ||
| Structure | 
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