| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50479070 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_509633 (CHEMBL1003961) |
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| IC50 | 33000±n/a nM |
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| Citation |  Zeng, LF; Jiang, XH; Sanchez, T; Zhang, HS; Dayam, R; Neamati, N; Long, YQ Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation. Bioorg Med Chem16:7777-87 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50479070 |
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| n/a |
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| Name | BDBM50479070 |
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| Synonyms: | CHEMBL465864 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H7F3O4 |
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| Mol. Mass. | 260.1661 |
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| SMILES | OC(=O)C(\O)=C\C(=O)c1ccc(cc1)C(F)(F)F |
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| Structure | 
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