| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
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| Ligand | BDBM50501882 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1805767 (CHEMBL4305126) |
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| IC50 | >10000±n/a nM |
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| Citation |  Liu, X; Wang, B; Chen, C; Qi, Z; Zou, F; Wang, J; Hu, C; Wang, A; Ge, J; Liu, Q; Yu, K; Hu, Z; Jiang, Z; Wang, W; Wang, L; Wang, W; Ren, T; Bai, M; Liu, Q; Liu, J Discovery of ( E)- N J Med Chem62:5006-5024 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-3 |
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| Name: | Serine/threonine-protein kinase pim-3 |
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| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
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| Type: | Protein |
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| Mol. Mass.: | 35888.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86V86 |
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| Residue: | 326 |
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| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
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| BDBM50501882 |
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| n/a |
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| Name | BDBM50501882 |
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| Synonyms: | CHEMBL4446361 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H18FN5O2 |
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| Mol. Mass. | 415.4197 |
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| SMILES | Fc1cccc(NC(=O)CC(=O)Nc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2)c1 |
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| Structure | 
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