| Reaction Details |
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 | Report a problem with these data |
| Target | Trehalase |
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| Ligand | BDBM50487994 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_916861 (CHEMBL3082109) |
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| IC50 | 707950±n/a nM |
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| Citation |  Qian, X; Liu, Z; Li, Z; Li, Z; Song, G Synthesis and quantitative structure-activity relationships of fluorine-containing 4,4-dihydroxylmethyl-2-aryliminooxazo(thiazo)lidines as trehalase inhibitors. J Agric Food Chem49:5279-84 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trehalase |
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| Name: | Trehalase |
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| Synonyms: | Alpha-trehalose glucohydrolase | TREH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66445.51 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_105438 |
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| Residue: | 583 |
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| Sequence: | MQRRTWGLHLLLLLGLGLGSWEALPPPCESQIYCHGELLRQVQMARLYQDDKQFVDMPLS
VAPDQVLQRFSELAQAHNFSIPQQELQDFIREHFQAVGQELQPWTPEDWKDSPQFLQKIL
DPKLRAWAGQLHQLWKKLGKKVKPEVLSHPERFSLIYSGHPFIVPGGRFVEFYYWDSYWV
MEGLLLSEMPGTVKGMLQNFLDLVQTYGHVPNGARVYYLQRSQPPLLSLMMERYVTQAND
TAFLRDNLETLALELDFWTKNRSISVSSGGKSYVLNRYHVPYGGPRPESYSKDAELAATL
SEGDHEALWAELKAGAESGWDFSSRWFVGGPNPDSLSSIRTSKLVPVDLNAFLCQAEELM
SNFYSRLGNDSQAEKYRNLRAQRMAAMKDILWDEEKGAWFDYDLENGKKNLEFYPSNLAP
LWAGCFSDPGDVDKALKYLEDSQILTYHYGIPTSLRKTGQQWDFPNAWAPLQDLVIRGLA
KSPSARAQEVAFQLAQNWIRTNFDVYSRRSAMYEKYDISNGGQPGGGGEYEVQEGFGWTN
GVVLMLLDRYGDRLSSGTQTVFLEPHCLTAALLLGLMLSLLPQ
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| BDBM50487994 |
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| n/a |
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| Name | BDBM50487994 |
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| Synonyms: | CHEMBL2270891 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H11F3N2O2S |
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| Mol. Mass. | 292.277 |
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| SMILES | OCC1(CO)CS\C(N1)=N/c1ccc(F)c(F)c1F |
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| Structure | 
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