| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50493207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_978402 (CHEMBL2421044) |
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| IC50 | >20000±n/a nM |
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| Citation |  Serrao, E; Xu, ZL; Debnath, B; Christ, F; Debyser, Z; Long, YQ; Neamati, N Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction. Bioorg Med Chem21:5963-72 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50493207 |
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| n/a |
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| Name | BDBM50493207 |
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| Synonyms: | CHEMBL2419620 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17N5O3 |
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| Mol. Mass. | 315.3272 |
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| SMILES | Oc1ccccc1NC(=O)c1nc[nH]c1C(=O)N1CCNCC1 |
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| Structure | 
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