| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50493583 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_987693 (CHEMBL2439561) |
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| IC50 | 0.700000±n/a nM |
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| Citation |  Zhang, J; Wang, JL; Yu, WF; Zhou, ZM; Tao, WC; Wang, YC; Xue, WZ; Xu, D; Hao, LP; Han, XF; Fei, F; Liu, T; Liang, AH Nonpeptidic angiotensin II AT? receptor antagonists derived from 6-substituted aminocarbonyl and acylamino benzimidazoles. Eur J Med Chem69:44-54 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM50493583 |
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| n/a |
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| Name | BDBM50493583 |
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| Synonyms: | CHEMBL2435829 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27N3O4 |
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| Mol. Mass. | 457.521 |
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| SMILES | CCCc1nc2c(C)cc(NC(=O)OC)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O |
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| Structure | 
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