| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 |
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| Ligand | BDBM321460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1810765 (CHEMBL4310225) |
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| IC50 | 3000±n/a nM |
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| Citation |  Wang, S; Tsui, V; Crawford, TD; Audia, JE; Burdick, DJ; Beresini, MH; Côté, A; Cummings, R; Duplessis, M; Flynn, EM; Hewitt, MC; Huang, HR; Jayaram, H; Jiang, Y; Joshi, S; Murray, J; Nasveschuk, CG; Pardo, E; Poy, F; Romero, FA; Tang, Y; Taylor, AM; Wang, J; Xu, Z; Zawadzke, LE; Zhu, X; Albrecht, BK; Magnuson, SR; Bellon, S; Cochran, AG GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. J Med Chem61:9301-9315 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 9 |
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| Name: | Bromodomain-containing protein 9 |
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| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66994.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108000 |
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| Residue: | 597 |
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| Sequence: | MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
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| BDBM321460 |
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| n/a |
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| Name | BDBM321460 |
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| Synonyms: | 3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-5-(morpholine-4-carbonyl)benzonitrile | US10183009, Example 50 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4O3 |
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| Mol. Mass. | 402.4458 |
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| SMILES | C=CCCn1cc(-c2cc(cc(c2)C(=O)N2CCOCC2)C#N)c2cc[nH]c2c1=O |
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| Structure | 
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