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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cell division cycle 7-related protein kinase | ||
| Ligand | BDBM50506350 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1825612 (CHEMBL4325376) | ||
| Kd | 0.424±n/a nM | ||
| Citation |  Kurasawa, O; Miyazaki, T; Homma, M; Oguro, Y; Imada, T; Uchiyama, N; Iwai, K; Yamamoto, Y; Ohori, M; Hara, H; Sugimoto, H; Iwata, K; Skene, R; Hoffman, I; Ohashi, A; Nomura, T; Cho, N Discovery of a Novel, Highly Potent, and Selective Thieno[3,2- J Med Chem63:1084-1104 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cell division cycle 7-related protein kinase | |||
| Name: | Cell division cycle 7-related protein kinase | ||
| Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 | ||
| Type: | Protein | ||
| Mol. Mass.: | 63908.16 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00311 | ||
| Residue: | 574 | ||
| Sequence: |
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| BDBM50506350 | |||
| n/a | |||
| Name | BDBM50506350 | ||
| Synonyms: | Simurosertib | Tak 931 | Tak-931 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H19N5OS | ||
| Mol. Mass. | 341.431 | ||
| SMILES | Cc1n[nH]cc1-c1cc2nc([nH]c(=O)c2s1)[C@@H]1CC2CCN1CC2 |wD:16.18,(23.9,-5.5,;23.5,-6.99,;22.05,-7.46,;22.05,-9,;23.5,-9.47,;24.42,-8.23,;25.96,-8.23,;26.79,-6.94,;28.26,-7.33,;29.55,-6.49,;30.92,-7.17,;31.02,-8.7,;29.74,-9.56,;29.74,-11.1,;28.36,-8.87,;26.92,-9.42,;32.26,-6.4,;32.26,-4.86,;33.59,-4.09,;34.93,-4.86,;34.93,-6.4,;33.59,-7.17,;33.99,-5.69,;33.19,-5.58,)| | ||
| Structure | 
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