| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50065581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60973 (CHEMBL671591) |
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| Ki | 32.3±n/a nM |
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| Citation |  Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Synthesis and pharmacological characterization of novel 6-fluorochroman derivatives as potential 5-HT1A receptor antagonists. J Med Chem41:2765-78 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50065581 |
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| n/a |
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| Name | BDBM50065581 |
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| Synonyms: | 8-{2-[4-(4-Chloro-phenyl)-butylamino]-ethoxy}-6-fluoro-chroman-4-one | CHEMBL96265 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23ClFNO3 |
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| Mol. Mass. | 391.864 |
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| SMILES | Fc1cc(OCCNCCCCc2ccc(Cl)cc2)c2OCCC(=O)c2c1 |
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| Structure | 
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