| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50068140 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146652 (CHEMBL754936) |
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| IC50 | 31±n/a nM |
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| Citation |  Liao, S; Alfaro-Lopez, J; Shenderovich, MD; Hosohata, K; Lin, J; Li, X; Stropova, D; Davis, P; Jernigan, KA; Porreca, F; Yamamura, HI; Hruby, VJ De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor. J Med Chem41:4767-76 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50068140 |
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| n/a |
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| Name | BDBM50068140 |
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| Synonyms: | 3-[(4-Benzyl-piperazin-1-yl)-biphenyl-4-yl-methyl]-phenol | CHEMBL356778 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H30N2O |
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| Mol. Mass. | 434.572 |
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| SMILES | Oc1cccc(c1)C(N1CCN(Cc2ccccc2)CC1)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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