| Reaction Details |
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 | Report a problem with these data |
| Target | Oxysterols receptor LXR-beta |
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| Ligand | BDBM50515030 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1859656 (CHEMBL4360512) |
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| EC50 | 19000±n/a nM |
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| Citation |  Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Identify liver X receptor ? modulator building blocks by developing a fluorescence polarization-based competition assay. Eur J Med Chem178:458-467 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxysterols receptor LXR-beta |
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| Name: | Oxysterols receptor LXR-beta |
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| Synonyms: | LXRB | Liver X receptor beta (NR1H2) | Liver X, LXR beta | NER | NR1H2 | NR1H2_HUMAN | Nuclear receptor NER | UNR | Ubiquitously-expressed nuclear receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50978.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55055 |
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| Residue: | 460 |
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| Sequence: | MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
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| BDBM50515030 |
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| n/a |
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| Name | BDBM50515030 |
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| Synonyms: | CHEMBL4442070 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N3O3 |
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| Mol. Mass. | 249.2658 |
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| SMILES | CCOC(=O)c1cn2nc[nH]c(=O)c2c1C(C)C |
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| Structure | 
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