| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50336977 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1920203 (CHEMBL4423048) |
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| Ki | 24±n/a nM |
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| Citation |  Härter, M; Kalthof, B; Delbeck, M; Lustig, K; Gerisch, M; Schulz, S; Kast, R; Meibom, D; Lindner, N Novel non-xanthine antagonist of the A Eur J Med Chem163:763-778 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50336977 |
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| n/a |
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| Name | BDBM50336977 |
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| Synonyms: | CHEMBL1672627 | N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14FN5O |
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| Mol. Mass. | 335.3351 |
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| SMILES | Fc1cnccc1-c1ncc(NC(=O)C2CC2)nc1-c1cccnc1 |
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| Structure | 
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