| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50152731 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1920576 (CHEMBL4423421) |
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| EC50 | 156±n/a nM |
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| Citation |  Li, Z; Chen, Y; Zhou, Z; Deng, L; Xu, Y; Hu, L; Liu, B; Zhang, L Discovery of first-in-class thiazole-based dual FFA1/PPAR? agonists as potential anti-diabetic agents. Eur J Med Chem164:352-365 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50152731 |
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| n/a |
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| Name | BDBM50152731 |
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| Synonyms: | CHEMBL3781779 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21NO5S |
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| Mol. Mass. | 411.471 |
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| SMILES | COc1ccc(cc1)-c1nc(C)c(COc2ccc3C(CC(O)=O)COc3c2)s1 |
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| Structure | 
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