| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50087548 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_214402 |
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| IC50 | 240±n/a nM |
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| Citation |  Albright, JD; Delos Santos, EG; Dusza, JP; Chan, PS; Coupet, J; Ru, X; Mazandarani, H The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-aroyl-2,4,5,6-tetrahydropyrazolo[3,4-d]thieno[3,2-b]azepines. Bioorg Med Chem Lett10:695-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM50087548 |
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| n/a |
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| Name | BDBM50087548 |
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| Synonyms: | CHEMBL350383 | N-[4-(4,5-Dihydro-2H-9-thia-1,2,6-triaza-cyclopenta[e]azulene-6-carbonyl)-phenyl]-2-methyl-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N4O2S |
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| Mol. Mass. | 428.506 |
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| SMILES | Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCc2c[nH]nc2-c2sccc12 |
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| Structure | 
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