| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50087544 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_226394 (CHEMBL846736) |
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| IC50 | 340±n/a nM |
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| Citation |  Albright, JD; Delos Santos, EG; Dusza, JP; Chan, PS; Coupet, J; Ru, X; Mazandarani, H The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-aroyl-2,4,5,6-tetrahydropyrazolo[3,4-d]thieno[3,2-b]azepines. Bioorg Med Chem Lett10:695-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40761.85 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | n/a |
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| Residue: | 371 |
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| Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
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| BDBM50087544 |
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| n/a |
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| Name | BDBM50087544 |
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| Synonyms: | 2-Chloro-N-[4-(4,5-dihydro-2H-9-thia-1,2,6-triaza-cyclopenta[e]azulene-6-carbonyl)-phenyl]-4-fluoro-benzamide | CHEMBL162588 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H16ClFN4O2S |
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| Mol. Mass. | 466.915 |
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| SMILES | Fc1ccc(C(=O)Nc2ccc(cc2)C(=O)N2CCc3c[nH]nc3-c3sccc23)c(Cl)c1 |
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| Structure | 
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