| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H4 receptor |
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| Ligand | BDBM50538681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1973780 (CHEMBL4606598) |
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| Ki | 31±n/a nM |
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| Citation |  Bartole, E; Grätz, L; Littmann, T; Wifling, D; Seibel, U; Buschauer, A; Bernhardt, G UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H J Med Chem63:5297-5311 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H4 receptor |
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| Name: | Histamine H4 receptor |
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| Synonyms: | HH4R | HRH4_MOUSE | Hrh4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44272.75 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Cell pellets from SK-N-MC cells transfected with mouse H4 receptor were used in binding assay. |
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| Residue: | 391 |
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| Sequence: | MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAIS
DFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAV
SYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTIT
MLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSN
PGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRG
RKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLY
PLCHRRFQKAFWKILCVTKQPALSQNQSVSS
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| BDBM50538681 |
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| n/a |
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| Name | BDBM50538681 |
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| Synonyms: | CHEMBL4595327 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H27N5 |
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| Mol. Mass. | 277.4084 |
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| SMILES | CN(C)[C@@H]1CCN(C1)c1ccnc(NCC(C)(C)C)n1 |r| |
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| Structure | 
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