Reaction Details | |||
---|---|---|---|
![]() | Report a problem with these data | ||
Target | Histone-lysine N-methyltransferase EZH2 | ||
Ligand | BDBM50541912 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1985527 (CHEMBL4618933) | ||
IC50 | 0.063000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Histone-lysine N-methyltransferase EZH2 | |||
Name: | Histone-lysine N-methyltransferase EZH2 | ||
Synonyms: | ENX-1 | EZH2 | EZH2_HUMAN | Enhancer of zeste homolog 2 (EZH2) | Histone-lysine N-methyltransferase EZH2 | KMT6 | Lysine N-methyltransferase 6 | ||
Type: | Protein | ||
Mol. Mass.: | 85367.84 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15910 | ||
Residue: | 746 | ||
Sequence: |
| ||
BDBM50541912 | |||
n/a | |||
Name | BDBM50541912 | ||
Synonyms: | CHEMBL4637572 | ||
Type | Small organic molecule | ||
Emp. Form. | C32H41FN4O3S | ||
Mol. Mass. | 580.756 | ||
SMILES | [H][C@@]1(CC[C@@H](CC1)N1CC(C1)OC1CC1)[C@@H](C)n1c(C)c(C(=O)NCc2c(SC)cc(C)[nH]c2=O)c2cccc(F)c12 |r,wU:4.7,1.0,wD:15.18,(42.35,-24.8,;41.6,-26.14,;40.82,-27.47,;41.6,-28.8,;43.14,-28.8,;43.9,-27.47,;43.13,-26.13,;43.9,-30.13,;43.51,-31.62,;45,-32.02,;45.39,-30.53,;45.76,-33.35,;45,-34.69,;43.67,-35.45,;45,-36.23,;40.82,-24.81,;41.59,-23.47,;39.29,-24.81,;38.26,-23.66,;38.59,-22.16,;36.85,-24.3,;35.52,-23.52,;35.53,-21.98,;34.19,-24.29,;32.85,-23.51,;31.52,-24.28,;31.52,-25.82,;32.85,-26.59,;32.85,-28.13,;30.19,-26.58,;28.86,-25.82,;27.52,-26.59,;28.86,-24.28,;30.19,-23.5,;30.19,-21.96,;37.02,-25.82,;35.99,-26.96,;36.45,-28.42,;37.96,-28.74,;38.98,-27.6,;39.74,-28.93,;38.52,-26.15,)| | ||
Structure | ![]() |