| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 52 |
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| Ligand | BDBM50554911 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2050975 (CHEMBL4705674) |
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| EC50 | 371±n/a nM |
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| Citation |  Wang, P; Felsing, DE; Chen, H; Stutz, SJ; Murphy, RE; Cunningham, KA; Allen, JA; Zhou, J Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior. J Med Chem63:13951-13972 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 52 |
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| Name: | G-protein coupled receptor 52 |
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| Synonyms: | GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41366.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108391 |
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| Residue: | 361 |
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| Sequence: | MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS
I
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| BDBM50554911 |
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| n/a |
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| Name | BDBM50554911 |
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| Synonyms: | CHEMBL4751311 | US20240059655, Compound PW0904 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H19F3N4O2S |
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| Mol. Mass. | 460.472 |
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| SMILES | OCCNC(=O)c1cccc2N(CCc12)c1cc(Sc2cccc(c2)C(F)(F)F)ncn1 |
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| Structure | 
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