| Reaction Details |
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 | Report a problem with these data |
| Target | Transitional endoplasmic reticulum ATPase |
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| Ligand | BDBM50558084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2061777 (CHEMBL4717030) |
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| Ki | 3500±n/a nM |
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| Citation |  Alverez, C; Bulfer, SL; Chakrasali, R; Chimenti, MS; Deshaies, RJ; Green, N; Kelly, M; LaPorte, MG; Lewis, TS; Liang, M; Moore, WJ; Neitz, RJ; Peshkov, VA; Walters, MA; Zhang, F; Arkin, MR; Wipf, P; Huryn, DM Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. ACS Med Chem Lett7:182-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transitional endoplasmic reticulum ATPase |
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| Name: | Transitional endoplasmic reticulum ATPase |
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| Synonyms: | TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 89300.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55072 |
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| Residue: | 806 |
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| Sequence: | MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLK
GKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPID
DTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDT
VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG
ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI
IFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF
GRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAAL
QAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIG
GLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFI
SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRV
INQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKAN
LRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAM
EVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGG
AGPSQGSGGGTGGSVYTEDNDDDLYG
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| BDBM50558084 |
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| n/a |
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| Name | BDBM50558084 |
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| Synonyms: | CHEMBL4799933 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O |
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| Mol. Mass. | 266.2979 |
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| SMILES | Cc1cc2cc(NC(=O)c3cccnc3N)ccc2[nH]1 |
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| Structure | 
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