| Reaction Details |
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 | Report a problem with these data |
| Target | Formyl peptide receptor 2 |
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| Ligand | BDBM50559840 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2070443 (CHEMBL4725977) |
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| EC50 | 1.4±n/a nM |
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| Citation |  Asahina, Y; Wurtz, NR; Arakawa, K; Carson, N; Fujii, K; Fukuchi, K; Garcia, R; Hsu, MY; Ishiyama, J; Ito, B; Kick, E; Lupisella, J; Matsushima, S; Ohata, K; Ostrowski, J; Saito, Y; Tsuda, K; Villarreal, F; Yamada, H; Yamaoka, T; Wexler, R; Gordon, D; Kohno, Y Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure. J Med Chem63:9003-9019 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Formyl peptide receptor 2 |
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| Name: | Formyl peptide receptor 2 |
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| Synonyms: | FPR2_MOUSE | Formyl peptide receptor 2 | Formylpeptide receptor-related sequence 2 | Fpr-rs2 | Fpr2 | Lipoxin A4 receptor-like protein | N-formylpeptide receptor-like 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39427.03 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_120178 |
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| Residue: | 351 |
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| Sequence: | MESNYSIHLNGSEVVVYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVT
TIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIVVDVNLFGSVFLIALIA
LDRCICVLHPVWAQNHRTVSLARKVVVGPWIFALILTLPIFIFLTTVRIPGGDVYCTFNF
GSWAQTDEEKLNTAITFVTTRGIIRFLIGFSMPMSIVAVCYGLIAVKINRRNLVNSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWFKETLLSGSYKILDMFVNPTSSLAYFNSCLNPM
LYVFMGQDFRERFIHSLPYSLERALSEDSGQTSDSSTSSTSPPADIELKAP
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| BDBM50559840 |
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| n/a |
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| Name | BDBM50559840 |
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| Synonyms: | CHEMBL4760897 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14ClF2N3O3S |
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| Mol. Mass. | 401.815 |
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| SMILES | COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 |r| |
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| Structure | 
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