Found 118 hits with Last Name = 'fukuchi' and Initial = 'k' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363909
(CHEMBL1946933)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2sc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H12F3N3O2S/c1-6-5-9(21)19-20-10(6)7-3-4-8(22-2)11-12(7)23-13(18-11)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
N-formyl peptide receptor 2
(Homo sapiens (Human)) | BDBM50559829
(CHEMBL4784510)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at FPR2 in human HL-60 cells assessed as reduction in chemoattractant induced chemotaxis by luminescence cell viability assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363909
(CHEMBL1946933)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2sc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H12F3N3O2S/c1-6-5-9(21)19-20-10(6)7-3-4-8(22-2)11-12(7)23-13(18-11)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363906
(CHEMBL1946747)Show SMILES COc1ccc(C2=NNC(=O)CC2C)n2cc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-7-5-11(22)19-20-12(7)8-3-4-9(23-2)13-18-10(6-21(8)13)14(15,16)17/h3-4,6-7H,5H2,1-2H3,(H,19,22) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363910
(CHEMBL1946934)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2cc(sc12)C(F)(F)F |t:6| Show InChI InChI=1S/C15H13F3N2O2S/c1-7-5-12(21)19-20-13(7)8-3-4-10(22-2)14-9(8)6-11(23-14)15(16,17)18/h3-4,6-7H,5H2,1-2H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363912
(CHEMBL1946936)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2[nH]c(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-6-5-9(22)20-21-10(6)7-3-4-8(23-2)12-11(7)18-13(19-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,18,19)(H,20,22) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363911
(CHEMBL1946935)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2ccc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C16H14F3N3O2/c1-8-7-13(23)21-22-14(8)9-3-5-11(24-2)15-10(9)4-6-12(20-15)16(17,18)19/h3-6,8H,7H2,1-2H3,(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363913
(CHEMBL1946937)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2cc(oc12)C(F)(F)F |t:6| Show InChI InChI=1S/C15H13F3N2O3/c1-7-5-12(21)19-20-13(7)8-3-4-10(22-2)14-9(8)6-11(23-14)15(16,17)18/h3-4,6-7H,5H2,1-2H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363905
(CHEMBL1946746)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2nc(nn12)C(F)(F)F |t:6| Show InChI InChI=1S/C13H12F3N5O2/c1-6-5-8(22)18-19-10(6)7-3-4-9(23-2)21-11(7)17-12(20-21)13(14,15)16/h3-4,6H,5H2,1-2H3,(H,18,22) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363911
(CHEMBL1946935)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2ccc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C16H14F3N3O2/c1-8-7-13(23)21-22-14(8)9-3-5-11(24-2)15-10(9)4-6-12(20-15)16(17,18)19/h3-6,8H,7H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363907
(CHEMBL1946748)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2oc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H12F3N3O3/c1-6-5-9(21)19-20-10(6)7-3-4-8(22-2)11-12(7)23-13(18-11)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363906
(CHEMBL1946747)Show SMILES COc1ccc(C2=NNC(=O)CC2C)n2cc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-7-5-11(22)19-20-12(7)8-3-4-9(23-2)13-18-10(6-21(8)13)14(15,16)17/h3-4,6-7H,5H2,1-2H3,(H,19,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363908
(CHEMBL1946932)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2nc(oc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H12F3N3O3/c1-6-5-9(21)19-20-10(6)7-3-4-8(22-2)12-11(7)18-13(23-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363910
(CHEMBL1946934)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2cc(sc12)C(F)(F)F |t:6| Show InChI InChI=1S/C15H13F3N2O2S/c1-7-5-12(21)19-20-13(7)8-3-4-10(22-2)14-9(8)6-11(23-14)15(16,17)18/h3-4,6-7H,5H2,1-2H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50363914
(CHEMBL1946938)Show InChI InChI=1S/C16H19N3O2/c1-4-11-8-13-12(5-6-15(21-3)19(13)9-11)16-10(2)7-14(20)17-18-16/h5-6,8-10H,4,7H2,1-3H3,(H,17,20) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50559840
(CHEMBL4760897)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human CYP3A4 |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363907
(CHEMBL1946748)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2oc(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H12F3N3O3/c1-6-5-9(21)19-20-10(6)7-3-4-8(22-2)11-12(7)23-13(18-11)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 5.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363908
(CHEMBL1946932)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2nc(oc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H12F3N3O3/c1-6-5-9(21)19-20-10(6)7-3-4-8(22-2)12-11(7)18-13(23-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 6.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363905
(CHEMBL1946746)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2nc(nn12)C(F)(F)F |t:6| Show InChI InChI=1S/C13H12F3N5O2/c1-6-5-8(22)18-19-10(6)7-3-4-9(23-2)21-11(7)17-12(20-21)13(14,15)16/h3-4,6H,5H2,1-2H3,(H,18,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363913
(CHEMBL1946937)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2cc(oc12)C(F)(F)F |t:6| Show InChI InChI=1S/C15H13F3N2O3/c1-7-5-12(21)19-20-13(7)8-3-4-10(22-2)14-9(8)6-11(23-14)15(16,17)18/h3-4,6-7H,5H2,1-2H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50559835
(CHEMBL4762030)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(F)c2)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human CYP3A4 |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50559838
(CHEMBL4790836)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)c(O)c2)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human CYP3A4 |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50559821
(CHEMBL4781596)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human CYP3A4 |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50559829
(CHEMBL4784510)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human CYP3A4 |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363914
(CHEMBL1946938)Show InChI InChI=1S/C16H19N3O2/c1-4-11-8-13-12(5-6-15(21-3)19(13)9-11)16-10(2)7-14(20)17-18-16/h5-6,8-10H,4,7H2,1-3H3,(H,17,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50363912
(CHEMBL1946936)Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2[nH]c(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-6-5-9(22)20-21-10(6)7-3-4-8(23-2)12-11(7)18-13(19-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,18,19)(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human PDE3A catalytic domain |
Bioorg Med Chem 20: 1644-58 (2012)
Article DOI: 10.1016/j.bmc.2012.01.033
BindingDB Entry DOI: 10.7270/Q2DB829P |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559818
(CHEMBL4743084)Show SMILES COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(C)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 76 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559819
(CHEMBL4793557)Show SMILES Fc1ccc(NC(=O)N[C@H]2[C@@H](CNC2=O)c2ccc(Cl)cc2F)cc1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559820
(CHEMBL4744835)Show SMILES COc1cc(F)c(cc1F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccc(F)cc1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559821
(CHEMBL4781596)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559822
(CHEMBL4753713)Show SMILES COc1cnc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559824
(CHEMBL4783963)Show SMILES CCc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559825
(CHEMBL4758129)Show SMILES Fc1ccc(NC(=O)N[C@H]2[C@@H](CNC2=O)c2c(F)cc(cc2F)C#N)cc1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559826
(CHEMBL4781488)Show SMILES CNc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559827
(CHEMBL4763824)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cccc(F)c2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559829
(CHEMBL4784510)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559830
(CHEMBL4758920)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559831
(CHEMBL4761554)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Br)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 96 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559832
(CHEMBL4742149)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(cc2)C#N)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559833
(CHEMBL4763673)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)cc2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559834
(CHEMBL4789579)Show SMILES COc1ccc(NC(=O)N[C@H]2[C@@H](CNC2=O)c2c(F)cc(OC)cc2F)cc1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559835
(CHEMBL4762030)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(F)c2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 820 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559836
(CHEMBL4755590)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(O)c2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 72 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559837
(CHEMBL4776349)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)c(O)c2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559838
(CHEMBL4790836)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)c(O)c2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559839
(CHEMBL4792002)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cn2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559840
(CHEMBL4760897)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559842
(CHEMBL4778725)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cc(C)ns2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 290 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
fMet-Leu-Phe receptor
(Homo sapiens (Human)) | BDBM50559843
(CHEMBL4749577)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cc3ccccc3s2)c(F)c1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
Formyl peptide receptor 2
(Mus musculus) | BDBM50559821
(CHEMBL4781596)Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r| | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC |
More data for this
Ligand-Target Pair | |
Search and Browse
