| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Anionic trypsin-2 |
|---|
| Ligand | BDBM50123416 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_213052 |
|---|
| IC50 | 86±n/a nM |
|---|
| Citation |  Huang, W; Zhang, P; Zuckett, JF; Wang, L; Woolfrey, J; Song, Y; Jia, ZJ; Clizbe, LA; Su, T; Tran, K; Huang, B; Wong, P; Sinha, U; Park, G; Reed, A; Malinowski, J; Hollenbach, SJ; Scarborough, RM; Zhu, BY Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors. Bioorg Med Chem Lett13:561-6 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Anionic trypsin-2 |
|---|
| Name: | Anionic trypsin-2 |
|---|
| Synonyms: | Prss2 | TRY2_RAT | Try2 | Trypsin II |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 26220.44 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_213052 |
|---|
| Residue: | 246 |
|---|
| Sequence: | MRALLFLALVGAAVAFPVDDDDKIVGGYTCQENSVPYQVSLNSGYHFCGGSLINDQWVVS
AAHCYKSRIQVRLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLN
ARVATVALPSSCAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKIT
DNMVCVGFLEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQ
DTIAAN
|
|
|
|---|
| BDBM50123416 |
|---|
| n/a |
|---|
| Name | BDBM50123416 |
|---|
| Synonyms: | ((5-Carbamimidoyl-benzo[b]thiophen-2-ylmethyl)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-sulfamoyl)-acetic acid ethyl ester | CHEMBL152881 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H33N5O5S2 |
|---|
| Mol. Mass. | 571.711 |
|---|
| SMILES | CCOC(=O)CS(=O)(=O)N(Cc1cc2cc(ccc2s1)C(N)=N)c1ccc(OC2CCN(CC2)C(C)=N)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
