| Reaction Details |
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 | Report a problem with these data |
| Target | Proto-oncogene tyrosine-protein kinase Src |
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| Ligand | BDBM50024270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_226200 (CHEMBL843326) |
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| IC50 | <10±n/a nM |
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| Citation |  Ikuina, Y; Amishiro, N; Miyata, M; Narumi, H; Ogawa, H; Akiyama, T; Shiotsu, Y; Akinaga, S; Murakata, C Synthesis and antitumor activity of novel O-carbamoylmethyloxime derivatives of radicicol. J Med Chem46:2534-41 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proto-oncogene tyrosine-protein kinase Src |
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| Name: | Proto-oncogene tyrosine-protein kinase Src |
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| Synonyms: | Proto-oncogene c-Src | SRC_RAT | Src | Tyrosine-protein kinase SRC | p60-Src | pp60c-src |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59976.76 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_453858 |
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| Residue: | 536 |
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| Sequence: | MGSNKSKPKDASQRRRSLEPAENVHGAGGAFPASQTPSKPASADGHRGPNAAFVPPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKY
LRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
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| BDBM50024270 |
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| n/a |
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| Name | BDBM50024270 |
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| Synonyms: | CHEMBL85612 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H34ClN3O7 |
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| Mol. Mass. | 584.06 |
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| SMILES | [H][C@@]12C[C@@H](C)OC(=O)c3c(O)cc(O)c(Cl)c3C\C(\C=C\C=C/[C@@]1([H])O2)=N\OCC(=O)Nc1ccc(cc1)N(CC)CC |c:22,t:20| |
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| Structure | 
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