| Reaction Details |
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 | Report a problem with these data |
| Target | DCN1-like protein 1 |
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| Ligand | BDBM50569321 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2108934 (CHEMBL4817609) |
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| IC50 | 21±n/a nM |
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| Citation |  Zhou, W; Xu, C; Dong, G; Qiao, H; Yang, J; Liu, H; Ding, L; Sun, K; Zhao, W Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction. Eur J Med Chem217:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DCN1-like protein 1 |
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| Name: | DCN1-like protein 1 |
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| Synonyms: | DCN1 | DCN1-like protein 1 | DCNL1_HUMAN | DCUN1 domain-containing protein 1 | DCUN1D1 | DCUN1L1 | Defective in cullin neddylation protein 1-like protein 1 | RP42 | SCCRO | Squamous cell carcinoma-related oncogene | Synonyms=DCN1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30118.96 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117443 |
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| Residue: | 259 |
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| Sequence: | MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL
DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ
EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA
YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI
DDFVEFARPQIAGTKSTTV
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| BDBM50569321 |
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| n/a |
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| Name | BDBM50569321 |
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| Synonyms: | CHEMBL4851208 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H47N5O4S |
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| Mol. Mass. | 585.801 |
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| SMILES | CCC(=O)N[C@@H](Cc1nc2ccc(cc2s1)C(C)C)C(=O)N[C@@H](CNC(=O)CCN1CCOCC1)C1CCCCC1 |r| |
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| Structure | 
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