| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50137744 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_161071 (CHEMBL771844) |
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| Ki | 270±n/a nM |
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| Citation |  Lamar, J; Victor, F; Snyder, N; Johnson, RB; Wang, QM; Glass, JI; Chen, SH Novel P4 truncated tripeptidyl alpha-ketoamides as HCV protease inhibitors. Bioorg Med Chem Lett14:263-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44361.04 |
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| Organism: | Human rhinovirus B |
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| Description: | ChEMBL_158953 |
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| Residue: | 401 |
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| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
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| BDBM50137744 |
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| n/a |
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| Name | BDBM50137744 |
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| Synonyms: | CHEMBL328740 | {(S)-1-[(1S,3aR,6aS)-4,4-Difluoro-1-(1-phenylaminooxalyl-butylcarbamoyl)-hexahydro-cyclopenta[c]pyrrole-2-carbonyl]-2,2-dimethyl-propyl}-carbamic acid isopropyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C30H42F2N4O6 |
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| Mol. Mass. | 592.6745 |
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| SMILES | CCCC(NC(=O)[C@@H]1[C@H]2CCC(F)(F)[C@H]2CN1C(=O)[C@@H](NC(=O)OC(C)C)C(C)(C)C)C(=O)C(=O)Nc1ccccc1 |
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| Structure | 
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