| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 5 |
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| Ligand | BDBM50576097 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2126459 (CHEMBL4835804) |
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| EC50 | 630±n/a nM |
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| Citation |  Doering, SR; Freeman, K; Debevec, G; Geer, P; Santos, RG; Lavoi, TM; Giulianotti, MA; Pinilla, C; Appel, JR; Houghten, RA; Ericson, MD; Haskell-Luevano, C Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign. J Med Chem64:5577-5592 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 5 |
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| Name: | Melanocortin receptor 5 |
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| Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36966.58 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P41149 |
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| Residue: | 325 |
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| Sequence: | MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGA
IVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDS
MICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIY
YESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITL
TMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQ
EMRRTFKEIVCCHGFRRPCRLLGGY
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| BDBM50576097 |
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| n/a |
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| Name | BDBM50576097 |
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| Synonyms: | CHEMBL4861482 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H59N7O |
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| Mol. Mass. | 545.8465 |
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| SMILES | [H][C@]1(CN([C@H](CC2CCCCC2)N2CCC[C@H]2CN2[C@H](CC(C)C)CNC2=N)C(=N)N1CCCC(C)C)[C@@H](C)O |r| |
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| Structure | 
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