| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50578337 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2132590 (CHEMBL4842105) |
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| EC50 | 98±n/a nM |
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| Citation |  Yan, W; Fan, L; Yu, J; Liu, R; Wang, H; Tan, L; Wang, S; Cheng, J 2-Phenylcyclopropylmethylamine Derivatives as Dopamine D J Med Chem64:17239-17258 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50578337 |
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| n/a |
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| Name | BDBM50578337 |
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| Synonyms: | CHEMBL4862770 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29ClN2O3 |
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| Mol. Mass. | 428.952 |
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| SMILES | COc1ccc(Cl)cc1[C@H]1C[C@@H]1CNCCCCOc1ccc2CCC(=O)Nc2c1 |r| |
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| Structure | 
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