| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50588208 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2186469 (CHEMBL5098551) |
|---|
| Ki | 0.430000±n/a nM |
|---|
| Citation |  Duan, W; Sun, Y; Wu, M; Zhang, Z; Zhang, T; Wang, H; Li, F; Yang, L; Xu, Y; Liu, ZJ; Hua, T; Nie, H; Cheng, J Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis. Eur J Med Chem226:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52868.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21554 |
|---|
| Residue: | 472 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50588208 |
|---|
| n/a |
|---|
| Name | BDBM50588208 |
|---|
| Synonyms: | CHEMBL5187099 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H38O3Si |
|---|
| Mol. Mass. | 402.6422 |
|---|
| SMILES | [H][C@@]12[#6]-[#6](-[#6]-[#8])=[#6]-[#6][C@@]1([H])C([#6])([#6])[#8]-c1cc(cc(-[#8])c21)[Si;v4]([#6])([#6])[#6]-[#6]-[#6]-[#6]-[#6]-[#6] |r,c:5| |
|---|
| Structure | 
|
|---|
Search and Browse
