| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50588196 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2186470 (CHEMBL5098552) |
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| Ki | 2.2±n/a nM |
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| Citation |  Duan, W; Sun, Y; Wu, M; Zhang, Z; Zhang, T; Wang, H; Li, F; Yang, L; Xu, Y; Liu, ZJ; Hua, T; Nie, H; Cheng, J Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis. Eur J Med Chem226:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50588196 |
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| n/a |
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| Name | BDBM50588196 |
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| Synonyms: | CHEMBL5194443 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H34O2Si |
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| Mol. Mass. | 382.6111 |
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| SMILES | [#6]-[#6]-[#6]-[#6]-[#6]-[#6][Si;v4]([#6])([#6])c1cc(-[#8])c-2c(-[#8]C([#6])([#6])c3ccc(-[#6])cc-23)c1 |
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| Structure | 
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