| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 14-3-3 protein eta |
|---|
| Ligand | BDBM50591822 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2201840 (CHEMBL5114548) |
|---|
| Kd | 35000±n/a nM |
|---|
| Citation |  Gao, Z; Fan, T; Chen, L; Yang, M; Wai Wong, VK; Chen, D; Liu, Z; Zhou, Y; Wu, W; Qiu, Z; Zhang, C; Li, Y; Jiang, Y Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3? protein. Eur J Med Chem238:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 14-3-3 protein eta |
|---|
| Name: | 14-3-3 protein eta |
|---|
| Synonyms: | 14-3-3 protein eta | 1433F_HUMAN | Protein AS1 | YWHA1 | YWHAH |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28205.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_110546 |
|---|
| Residue: | 246 |
|---|
| Sequence: | MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW
RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK
VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS
VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE
EAGEGN
|
|
|
|---|
| BDBM50591822 |
|---|
| n/a |
|---|
| Name | BDBM50591822 |
|---|
| Synonyms: | CHEMBL5174718 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H32N2O3 |
|---|
| Mol. Mass. | 456.576 |
|---|
| SMILES | COc1cccc(CNCc2c(C(O)=O)n(Cc3ccc(C)cc3)c3cc(ccc23)C(C)C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
