| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin L2 |
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| Ligand | BDBM50165425 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306562 (CHEMBL829137) |
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| IC50 | 340±n/a nM |
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| Citation |  Barrett, DG; Catalano, JG; Deaton, DN; Long, ST; McFadyen, RB; Miller, AB; Miller, LR; Wells-Knecht, KJ; Wright, LL A structural screening approach to ketoamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett15:2209-13 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin L2 |
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| Name: | Cathepsin L2 |
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| Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V |
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| Type: | Enzyme |
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| Mol. Mass.: | 37341.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60911 |
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| Residue: | 334 |
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| Sequence: | MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
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| BDBM50165425 |
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| n/a |
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| Name | BDBM50165425 |
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| Synonyms: | CHEMBL195963 | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-(1,2,3,4-tetrahydro-naphthalen-1-yl) ester |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N2O4 |
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| Mol. Mass. | 436.5433 |
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| SMILES | CCCC[C@H](NC(=O)O[C@H]1CCCc2ccccc12)C(=O)C(=O)N[C@H](C)c1ccccc1 |
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| Structure | 
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