Ki Summary

Reaction Details

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Target

P-selectin

Ligand

BDBM50168303

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_306414 (CHEMBL827227)

IC50

19500000±n/a nM

Citation

Girard, C; Dourlat, J; Savarin, A; Surcin, C; Leue, S; Escriou, V; Largeau, C; Herscovici, J; Scherman, D Sialyl Lewis(x) analogs based on a quinic acid scaffold as the fucose mimic. Bioorg Med Chem Lett15:3224-8 (2005) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

P-selectin

Name:

P-selectin

Synonyms:

Type:

PROTEIN

Mol. Mass.:

90834.61

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1438999

Residue:

830

Sequence:

MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGLQCPALTTPGQGTMYCRHHPG
TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP

BDBM50168303

n/a

Name

BDBM50168303

Synonyms:

3-Hydroxy-2-[((3R,5R)-1,3,5-trihydroxy-4-(S)-hydroxy-cyclohexanecarbonyl)-amino]-propionic acid | CHEMBL193022

Type

Small organic molecule

Emp. Form.

C10H17NO8

Mol. Mass.

279.2439

SMILES

OC[C@H](NC(=O)[C@@]1(O)C[C@@H](O)[C@H](O)[C@H](O)C1)C(O)=O |wU:6.6,11.11,13.13,wD:6.5,2.2,9.9,(1.73,1.74,;.4,.97,;.4,-.57,;1.73,-1.34,;3.06,-.57,;3.06,.97,;4.39,-1.34,;5.74,-.57,;3.06,-2.11,;3.06,-3.66,;1.73,-4.44,;4.39,-4.43,;4.39,-5.97,;5.74,-3.66,;7.08,-4.44,;5.74,-2.11,;-.93,-1.34,;-2.28,-.57,;-.93,-2.89,)|

Structure