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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(1A) dopamine receptor | ||
| Ligand | BDBM50535448 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2215493 (CHEMBL5128625) | ||
| EC50 | 20±n/a nM | ||
| Citation |  Zhong, Z; He, X; Ge, J; Zhu, J; Yao, C; Cai, H; Ye, XY; Xie, T; Bai, R Discovery of small-molecule compounds and natural products against Parkinson's disease: Pathological mechanism and structural modification. Eur J Med Chem237:0 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(1A) dopamine receptor | |||
| Name: | D(1A) dopamine receptor | ||
| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 49303.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21728 | ||
| Residue: | 446 | ||
| Sequence: |
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| BDBM50535448 | |||
| n/a | |||
| Name | BDBM50535448 | ||
| Synonyms: | CHEMBL4469983 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H14FN3O3 | ||
| Mol. Mass. | 351.3312 | ||
| SMILES | Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3occc23)cc1F |(54.06,-8.22,;54.05,-6.68,;55.38,-5.9,;55.37,-4.36,;54.02,-3.6,;54.01,-2.06,;52.7,-4.38,;51.36,-3.62,;52.71,-5.91,;51.39,-6.69,;50.04,-5.93,;48.71,-6.71,;48.73,-8.24,;47.4,-9.01,;47.41,-10.55,;48.74,-11.32,;48.75,-12.87,;47.41,-13.64,;46.07,-12.87,;44.61,-13.34,;43.7,-12.1,;44.61,-10.85,;46.08,-11.33,;50.06,-9.01,;51.39,-8.23,;52.73,-9,)| | ||
| Structure | 
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