| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50595104 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2215516 (CHEMBL5128648) |
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| EC50 | 0.870000±n/a nM |
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| Citation |  Zhong, Z; He, X; Ge, J; Zhu, J; Yao, C; Cai, H; Ye, XY; Xie, T; Bai, R Discovery of small-molecule compounds and natural products against Parkinson's disease: Pathological mechanism and structural modification. Eur J Med Chem237:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50595104 |
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| n/a |
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| Name | BDBM50595104 |
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| Synonyms: | CHEMBL5192367 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38N4O |
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| Mol. Mass. | 482.6596 |
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| SMILES | CCCN(CCN1CCN(CC1)c1ccc2c(c1)[nH]c1ccccc21)[C@H]1CCc2c(O)cccc2C1 |r| |
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| Structure | 
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