| Reaction Details |
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 | Report a problem with these data |
| Target | Envelope glycoprotein gp160 |
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| Ligand | BDBM50596508 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2220590 (CHEMBL5133924) |
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| IC50 | >100000±n/a nM |
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| Citation |  Tsuji, K; Kobayakawa, T; Konno, K; Masuda, A; Takahashi, K; Ohashi, N; Yoshimura, K; Kuwata, T; Matsushita, S; Harada, S; Tamamura, H Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors. Bioorg Med Chem56:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Envelope glycoprotein gp160 |
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| Name: | Envelope glycoprotein gp160 |
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| Synonyms: | envelope glycoprotein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 91798.58 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | gi_45357394 |
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| Residue: | 814 |
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| Sequence: | MRVKGIRRNYQHLWRWGTMLLGMLMICSAKEQLWVTAYYGVPVWKEATTTLFCASDAKAY
DTEVHNVWATHACVPTDPNPREVVMGNVTEEFNIWNNSMVEQMHEDIISLWDESLKPCVK
LTPLCVTFNCTNYNGTRNGTTTEPPEVKNCTTKETGIKNCSFNIATSGVEDRFKKEYALL
YTADIVQIDNSSINYTLIGCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGK
GPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEVVIRSDNFSDNAKTIIVQLKDPVVINCT
RPNNNTRKGIRIGPGRTFYTTERIIGDIRQAHCNISRTQWNNTLRLIAAKLKKQFNNKTI
IFRNSSGGDPEIVMHSFNCGGEFFYCNTTQLFNSTWVHNNTWVHNNTGNDTEEGTITLPC
RIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLILTRDGGNTSSNNETFRPGGGDMRDN
WRSELYKYKVVKIEPLGVAPTKARRRVVQREKRAVGMLGAMFLGFLGAAGSTMGAASLAL
TVQARQVVSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLGDQQLLGIWG
CSGKLICTTAVPWNDSWSNKSLKYIWDNMTWMQWEKEIDIHVDTIYQLLEASQYQQEKNE
KDLLELDKWESLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSL
QTRLPTQRGPDRPEGIEEEGGERQRHIRSISEWILNNYPGRPAEPVPLQLPPLERLTLDC
NEDCGTSGTQGVGSPQVFVESPPVLESGTKEECC
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| BDBM50596508 |
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| n/a |
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| Name | BDBM50596508 |
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| Synonyms: | CHEMBL5206172 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H34ClF9N8O9 |
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| Mol. Mass. | 809.035 |
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| SMILES | OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NC(=N)NCCCCC(=O)NCCN1CCC(CC1)NC(=O)C(=O)Nc1ccc(Cl)cn1 |
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| Structure | 
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